Is a research scientist at INSERM who specializes in vascular biology. His work primarily focuses on the cellular and molecular mechanisms regulating angiogenesis and vascular remodeling, with particular emphasis on connexins—key proteins that form gap junctions between cells. After completing his PhD at the University of Lausanne and a postdoctoral fellowship in the Department of Vascular Surgery at Lausanne University Hospital, Dr. Alonso joined the University of Bordeaux as a laureate of the Investments for the Future Program, IdEx Bordeaux, to establish his research on the role of connexin channels within the microvasculature, in the lab of Dr. Elisabeth Génot. His research has since expanded to include the study of interactions between endothelial cells and the extracellular matrix. He contributed to the characterization of specialized structures called podosomes in endothelial cells, examined in both physiological and pathological contexts such as cancer and vascular diseases. He then focused his work on the extracellular matrix protein fibrillin and was the first to establish its involvement in angiogenesis. At BioTis, Dr. Alonso employs diverse experimental models (in vitro, in vivo, and ex vivo), combined with advanced molecular biology and imaging techniques, to investigate the dynamics of vascular network formation and maturation. His overarching goal is to identify novel therapeutic targets for vascular diseases and contribute to the development of innovative strategies in regenerative medicine.
